VERDI study metadata dictionary

This page gives a comprehensive overview of the quantitative studies of COVID-19 and mpox which are part of VERDI. It includes details of the study designs, settings, populations included and data collected.

Click on a study name to learn more and find the data dictionaries.

The table below lists all quantitative studies included in VERDI, including their design, countries and populations included, and whether they collect COVID-19 or mpox-related clinical-epidemiological and laboratory data.

 

Title Study status at Oct 2025 Design Countries included Primary population Collects COVID-19 clin-epi data Collects COVID-19 lab data Collects Mpox clin-epi data Collects Mpox lab data
Study 1 - Clalit Ongoing Linked Electronic Medical Record (EMR) Israel Pregnant women & children ✅ ✅
Study 2 - DIAMONDS Closed Cohort Australia, Austria, France, Gambia, Germany, Greece, Italy, Latvia, Nepal, Netherlands, Spain, Switzerland, Slovenia, Taiwan, UK Hospitalised children ✅ ✅
Study 3 - England National Registry Ongoing Linked Electronic Medical Record (EMR) England 0-17 years; linked maternal records ✅ ✅
Study 5 - RECoVER Europe Closed Cohort Netherlands Households ✅ ✅
Study 6 - Influenzanet digital cohort Ongoing Cohort Italy, France, Belgium Self-selected volunteers from the general population ✅ ✅
Study 7 - Norwegian National Registries Ongoing Linked Electronic Medical Record (EMR) Norway Pregnant women & children ✅ ✅
Study 8 - Pedianet Ongoing Linked EMR Veneto region, and all of Italy Children ✅ ✅
Study 9a - Stellenbosch COVID Kids Closed Cohort South Africa Children with presumptive COVID-19 ✅ ✅
Study 9b - Stellenbosch Umoya Closed Cohort South Africa Children with presumptive TB ✅ ✅
Study 9c - MUCO Kids Closed Cohort South Africa Children with respiratory tract infections ✅ ✅
Study 10 - Swiss School Cohort Closed Cohort Switzerland Schoolchildren ✅ ✅
Study 11a - Thai household Mahidol Closed Cohort Thailand Households ✅ ✅
Study 11b - Thai COVID-19 Cohort EMR Ongoing Linked Electronic Medical Record (EMR) Thailand Pregnant women & children ✅ ✅
Study 11c - Thai household CMU Closed Cohort Thailand Households ✅ ✅
Study 12 - Western Cape Province Ongoing Linked Electronic Medical Record (EMR) South Africa Pregnant women & children ✅ ✅
Study 13 - Mpox adult registry Closed Cohort France, Poland, Spain, UK Adult STI clinic attenders ✅ ✅
Study 15 - Mpox paediatric registry Closed Cohort Democratic Republic of the Congo, Ghana, Mexico, Nigeria, Spain, USA 0-17 years ✅ ✅
Study 18 - DEVHISE Closed Cross-sectional Italy Hospitalised children & healthy adults ✅ ✅
Study 19 - Estonia Ongoing Linked Electronic Medical Record (EMR) Estonia Entire population ✅ ✅
Study 20 - ULiège Closed Cohort Belgium Adult STI clinic attenders ✅ ✅

This table presents the study metadata as an overview of the key data on clinical-epidemiological variables collected by each VERDI study on COVID-19, by domain and construct.

All studies included demographic data, most hospitalisation data, and fewer studies primary care and outpatient data. Indicators of health status were commonly collected, and details of COVID-19 vaccines and symptoms were almost universally collected. Pregnancy and birth data were limited to studies which specifically focussed on these populations, and most studies collected mortality data.

 

Study 1 - Clalit Study 2 - Diamonds Study 3 - England National Registry Study 5 - RECoVER Europe Study 6 - InfluenzaNet digital cohort Study 7 - Norway National Registries Study 8 - Pedianet Italy Study 9a - Stellenbosch COVID kids Study 9b - Stellenbosch Umoya Study 10 - Swiss School cohort Study 11a - Thai household cohort (MU) Study 11b - Thai COVID-19 Cohort EMR Study 11c - Thai household cohort (CMU) Study 12 - Western Cape Province Study 19a - Estonia National SARS-CoV-2 Sequencing cohort Study 19b - Estonia Pregnancy & Newborn cohort Study 19c - Estonia Children cohort
Demographics
Date of birth (full or MM/YY) ✅ ✅ ✅   ✅ ✅ ✅ ✅ ✅   ✅ ✅ ✅ ✅ ✅ ✅ ✅
Age at contact     ✅ ✅ ✅ ✅ ✅     ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅
Sex / gender ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅   ✅ ✅ ✅ ✅ ✅ ✅ ✅
Country of birth ✅     ✅   ✅ ✅ ✅ ✅   ✅ ✅ ✅        
Ethnic group / race / population sector ✅ ✅ ✅     ✅   ✅ ✅     ✅     ✅    
Income level           ✅                    
Employment / occupation         ✅ ✅         ✅ ✅ ✅     ✅  
Other socio-economic status proxy   ✅ ✅   ✅   ✅ ✅ ✅              
Education level       ✅ ✅ ✅ ✅       ✅ ✅ ✅     ✅  
Civil status ('marital')     ✅   ✅ ✅           ✅          
Locality (of health care provision)   ✅ ✅   ✅ ✅ ✅         ✅   ✅ ✅    
Locality (of residence) ✅   ✅ ✅ ✅ ✅ ✅     ✅ ✅ ✅   ✅   ✅
Household size       ✅ ✅     ✅ ✅   ✅ ✅        
Household composition       ✅ ✅ ✅ *   ✅ ✅   ✅ ✅        
*linkage of siblings, mothers-fathers-children
Hospitalisation
Admission / discharge dates or duration ✅ ✅ ✅   ✅ ✅ ✅ ✅       ✅   ✅ ✅ ✅ ✅
Episode dates   ✅ ✅   ✅ ✅   ✅           ✅ ✅    
Episode type (e.g., general; birth) ✅   ✅     ✅           ✅   ✅      
Diagnosis (e.g., codes) ✅ ✅ ✅     ✅ ✅         ✅   ✅ ✅ ✅  
Procedures (e.g., codes)   ✅ ✅     ✅               ✅ # ✅    
Procedures dates   ✅ ✅     ✅               ✅ # ✅    
Dispensed medications   ✅       ✅   ✅ ✅         ✅ ?    
ICU admission   ✅ ✅ * ✅     ✅ ✅ ✅         ✅ ✅ ✅ ✅
Admission type (planned/emergency)   ✅ ✅         ✅ ✅                
Hospitalisation for COVID-19 ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅   ✅   ✅ ✅ ✅ ✅ ✅
*derived, # subset
Primary care, outpatient care
Date of visit / contact ✅   ✅ # ✅ ✅ ✅ ✅     ✅ ✅ ✅ ✅ ✅ ?    
Diagnosis codes ✅   ✅ #     ✅ ✅         ✅         ✅
Dispensed medications codes ✅   ✅ #     ✅ ✅             ✅      
Dispensed medications date ✅   ✅ #     ✅ ✅             ✅      
Primary care utilisation summary           ✅ *               ✅      
# subset; * derived
Health status and exposures
Height ✅ ✅   ✅     ✅ ✅ ✅   ✅   ✅     ✅  
Weight ✅ ✅   ✅     ✅ ✅ ✅   ✅   ✅     ✅  
Date of anthropometrics ✅ ✅         ✅ ✅ ✅   ✅   ✅        
Chronic / co-morbid conditions~ ✅ ✅ ✅ ~~ ✅   ✅ ✅ ✅ ✅   ✅ ✅ ✅ ✅   ✅ ✅
Medications for chronic conditions ✅     ✅ ✅ ✅ ✅ ✅ ✅   ✅   ✅ ✅      
Smoker in household       ✅       ✅ ✅   ✅   ✅        
Current smoker ✅ ✅   ✅ ✅           ✅   ✅     ✅  
~ can include obesity ~~generated, based on hospitalisations only (primary care in subset)
Vaccines
COVID-19 vaccine (timing, doses) ✅ ✅   ✅ ✅ ✅ ✅ ✅ ✅   ✅ ✅ ✅ ✅ ✅ ✅ ✅
Type of COVID-19 vaccine ✅ ✅   ✅ ✅ ✅ ✅       ✅ ✅ ✅ ✅ ✅ ✅ ✅
Other vaccinations / vaccination history ✅       ✅ ✅ ✅ ✅ ✅         ✅      
COVID-19 symptoms & contacts
COVID-19 episodes ✅ ✅ ✅ ** ✅ ✅ ✅ ✅ ✅   ✅ ✅ ✅ ** ✅ ✅   ✅ ✅
COVID-19 symptoms (type, severity, duration) ✅ ✅   ✅ ✅   ✅ ✅     ✅   ✅   ✅    
Influenza-like symptoms (type, timing, duration)       ✅ ✅     ✅     ✅   ✅        
COVID-19 health-seeking behaviour       ✅ ✅     ✅     ✅   ✅        
COVID-19 contacts in household       ✅ ✅ ✅   ✅     ✅   ✅        
Medications during C-19 episode ✅ ✅   ✅ ✅ ✅ ✅ ✅     ✅   ✅ ✅      
** if hospitalised (all) or if primary care consultation (subset for England)
Pregnancy & birth
Date of delivery ✅   ✅     ✅           ✅   ✅ ✅ ✅  
Length of gestation     ✅     ✅ ✅ #         ✅     ✅ ✅  
Birthweight     ✅     ✅ ✅ #               ✅ ✅  
Maternal age at delivery ✅   ✅     ✅           ✅   ✅ ✅ ✅  
Pregnancy complications     ✅ ^     ✅           ✅   ✅ ^ ✅ ✅  
Smoking pre-pregnancy ✅         ✅                      
Vaccines in pregnancy (non-COVID-19) ✅         ✅                 ✅    
Parity / nulliparity     ✅ ~     ✅           ✅     ✅ ✅  
Pre-pregnancy body mass index ✅         ✅                   ✅  
Pregnancy outcome (e.g. miscarriage)     ✅     ✅           ✅   ✅ ✅ ✅  
Mode of delivery     ✅ ~     ✅           ✅   ✅   ✅  
Sex of baby ✅   ✅     ✅               ✅ ✅ ✅  
Congenital anomalies     ✅ ~     ✅                 ✅ ✅  
Other newborn complications     ✅     ✅                 ✅ ✅  
Placental weight           ✅                      
Antenatal care usage           ✅ ~           ✅   ✅      
Currently pregnant ✅       ✅ ✅ ~         ✅   ✅ ✅      
^if results in hospitalisation; # for included children; ~derived/estimated
Death
Date of / age at death ✅ ✅ ✅     ✅ ✅ ✅ ✅     ✅   ✅ ✅ ✅ ✅
Cause of death   ✅ ✅     ✅ ✅ ✅ ✅ ~~     ✅   ✅ ✅ ✅ ✅
~~ COVID-19 / non-COVID-19
COVID-19 laboratory tests
Sample type tested       ✅ ✅     ✅ ✅ ✅ ✅   ✅ ✅      
Sample / specimen collection date     ✅ ✅       ✅ ✅ ✅ ✅   ✅ ✅ ✅    
SARS-CoV-2 PCR test date ✅ ✅ ✅ ✅   ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅
SARS-CoV-2 PCR pos / neg result ✅ ✅ ✅ ~ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅ ✅
SARS-CoV-2 PCR Ct Value       ✅       ✅ ~~ ✅ ~~   ✅   ✅   ✅    
SARS-CoV-2 LFT test date     ✅ ✅     ✅       ✅ ✅ ✅ ✅   ✅  
SARS-CoV-2 LFT test result     ✅ ✅     ✅       ✅ ✅ ✅ ✅   ✅  
Serology test date ✅     ✅             ✅   ✅        
Serology test results ✅     ✅   ✅         ✅   ✅        
SARS- COV-2 genomic test results               ✅ ~~     ✅   ✅        
SARS- COV-2 variant/ lineage           ✅ ~~   ✅ ~~     ✅   ✅   ✅ ✅  
Other lab tests   ✅                              
~negative tests only available for a subset; ~~results available for subset
COVID-19 sample collection / storage
Sample type collected       ✅       ✅ ✅   ✅   ✅        
Sample collection date       ✅       ✅ ✅   ✅   ✅        
Sample collection time       ✅       ✅ ✅                
Sample processing               ✅ ✅       ✅        
Sample quality               ✅ ✅       ✅        
Consent to use research sample   ✅           ✅     ✅   ✅        
Consent to share research sample   ✅                 ✅            

This table presents the study metadata as an overview of the key data on clinical-epidemiological variables collected by each VERDI study on mpox, by domain and construct.

 
 

  Study 13 - Mpox adult registry Study 15 - Mpox paediatric registry Study 18 - DEVHISE study Study 20 - ULiège mpox study
Demographics
Date of birth ✅ *     ✅
Age at contact ✅ ✅ ✅
Sex  ✅ ✅ ✅ ✅
Gender ✅ ✅   ✅
Ethnic group ✅ ✅  
Locality (of registration/ health care setting) ✅ ✅ ✅
Locality of residence       ✅
*year of birth
Health status and exposures
Height   ✅  
Weight   ✅  
Date of anthropometrics   ✅  
HIV status, timing of HIV diagnosis  ✅ ~ ✅ o   ✅ ~
HIV treatment ✅ ✅  
HIV pre-exposure prophylaxis ✅ ~     ✅ ~
HIV-related lab tests (HIV RNA, CD4) ✅     ✅
Other co-morbid conditions / co-infections ✅ ✅ ✅ ✅
Medications for other chronic conditions ✅ ✅  
Current smoker   ✅  
Risk factors for mpox acquisition ✅ ✅   ✅ #
~study restricted to those living with HIV or receiving PrEP; # study restricted to MSM; °diagnosis date not available
Mpox/ other infections presentation, symptoms, medications, hospitalisation
Date of symptom onset ✅ ✅ °°    ✅
Signs and symptoms  ✅ ✅   ✅
Lesion assessment ✅ ✅  
Lesion resolution ✅    
Outpatient facility presentation dates   ✅ °°   
Hospitalisation dates ✅ ✅ °°   
ICU admission   ✅  
Procedures and dates   ✅ °°°  
Complications ✅ ✅  
Medications (type, dates / duration) ✅ ✅  
Medical management       ✅
Imaging findings*   ✅  
Severe disease indicators ✅    
*exposed infants and pregnancy ultrasounds; °° dates are not collected but timing is measured as year/week or in relation to presentation  °°°procedures dates not available
Mpox/ other infections outcomes, death
Outcome at discharge from care ✅ ✅  
Sequelae   ✅  
Date  of / age at death ✅ ✅  
Cause of death ✅ * ✅ #  
Place of death (i.e., setting)   ✅ #  
*if mpox-related; # subset only (maternal record)
Vaccines
Mpox / orthopoxvirus vaccine doses and dates ✅ ✅   ✅
Vaccine administration route   ✅   ✅
Vaccine history   ✅ # ✅ ✅
# subset only (maternal record)
Pregnancy & birth
Pregnancy dates, length of gestation   ✅  
Number of fetuses   ✅  
Maternal age at delivery   ✅  
Pregnancy complications   ✅  
Pregnancy outcome    ✅  
Medications in pregnancy   ✅  
Vaccines in pregnancy   ✅  
Parity / gravidity   ✅  
Smoking    ✅  
Mpox testing in pregnancy    ✅  
Mode of delivery   ✅  
Sex of baby   ✅  
Infant anthropometrics at birth   ✅  
Congenital anomalies   ✅  
Mpox/ other infections diagnostics
Sample type   ✅   ✅
Sample date       ✅
Type of PCR test   ✅  
PCR test date ✅     ✅
PCR result pos / neg ✅ ✅   ✅
PCR Ct value   ✅  
Type of serology test   ✅   ✅
Serology test date      
Serology result   ✅   ✅
Other lab tests   ✅  
Mpox/ other infections sample collection / storage
Sample type collected     ✅ ✅
Sample collection date     ✅
Sample collection time     ✅
Sample processing     ✅
Sample quality     ✅
Consent to use research sample      
Consent to share research sample