Stellenbosch COVID Kids Study

Study profile

Description

The COVID Kids Study is a cohort study conducted in Cape Town, South Africa, aimed at monitoring children aged 0-13 years presenting to Tygerberg Hospital with respiratory illness during the COVID-19 pandemic, and their household contacts.

Countries involved: South Africa

Sample size: 354 children

Related publications:

Redfern A, van der Zalm MM, Lishman J, Goussard P, Smit L, Dagan R, Barday M, Mare M, Claassen M, Van Zyl G, Rabie H, Verhagen LM. Clinical Presentation and Outcome of Acute Respiratory Illnesses in South African Children During the COVID-19 Pandemic. Pediatr Infect Dis J. 2023;42(8):672-678. doi:10.1097/INF.0000000000003951
Bekker C, Dewandel I, Redfern A, McKenzie C, Lishman J, Verhagen LM, Claassen M, Wilson S, Dunbar R, Bosch C, van Zyl G, Preiser W, Goussard P, Rabie H, van der Zalm MM. Clinical spectrum of disease and outcomes in children with Omicron SARS-COV-2 infection in Cape Town, South Africa. IJTLD Open. 2024;1(1):27-33. Published 2024 Jan 1. doi:10.5588/ijtldopen.23.0053
Anthony MG, Hoddinott G, Van Niekerk M, Dewandel I, McKenzie C, Bekker C, Rabie H, Redfern A, van der Zalm MM. The socioeconomic impact of the COVID-19 lockdown on families affected by childhood respiratory illnesses in Cape Town, South Africa. PLOS Glob Public Health. 2024;4(3):e0003020. Published 2024 Mar 28. doi:10.1371/journal.pgph.0003020

Metadata collected

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	Data collected?
Demographics
Date of birth (full or MM/YY)	✅
Age at contact
Sex / gender	✅
Country of birth	✅
Ethnic group / race / population sector	✅
Income level
Employment / occupation
Other socio-economic status proxy	✅
Education level
Civil status (‘marital’)
Locality (of health care provision)
Locality (of residence)
Household size	✅
Household composition	✅

Hospitalisation
Admission / discharge dates or duration	✅
Episode dates	✅
Episode type (e.g., general; birth)
Diagnosis (e.g., codes)
Procedures (e.g., codes)
Procedures dates
Dispensed medications	✅
ICU admission	✅
Admission type (planned/emergency)	✅
Hospitalisation for COVID-19	✅

Primary care, outpatient care
Date of visit / contact
Diagnosis codes
Dispensed medications codes
Dispensed medications date
Primary care utilisation summary

Health status and exposures
Height	✅
Weight	✅
Date of anthropometrics	✅
Chronic / co-morbid conditions~	✅
Medications for chronic conditions	✅
Smoker in household	✅
Current smoker
~ can include obesity

Vaccines
COVID-19 vaccine (timing, doses)	✅
Type of COVID-19 vaccine
Other vaccinations / vaccination history	✅

COVID-19 symptoms & contacts
COVID-19 episodes	✅
COVID-19 symptoms (type, severity, duration)	✅
Influenza-like symptoms (type, timing, duration)	✅
COVID-19 health-seeking behaviour	✅
COVID-19 contacts in household	✅
Medications during C-19 episode	✅

Pregnancy & birth
Date of delivery
Length of gestation
Birthweight
Maternal age at delivery
Pregnancy complications
Smoking pre-pregnancy
Vaccines in pregnancy (non-COVID-19)
Parity / nulliparity
Pre-pregnancy body mass index
Pregnancy outcome (e.g. miscarriage)
Mode of delivery
Sex of baby
Congenital anomalies
Other newborn complications
Placental weight
Antenatal care usage
Currently pregnant

Death
Date of / age at death	✅
Cause of death	✅

COVID-19 laboratory tests
Sample type tested	✅
Sample / specimen collection date	✅
SARS-CoV-2 PCR test date	✅
SARS-CoV-2 PCR pos / neg result	✅
SARS-CoV-2 PCR Ct Value	✅ ~~
SARS-CoV-2 LFT test date
SARS-CoV-2 LFT test result
Serology test date
Serology test results
SARS- COV-2 genomic test results	✅ ~~
SARS- COV-2 variant/ lineage	✅ ~~
Other lab tests
~~results available for subset

COVID-19 sample collection / storage
Sample type collected	✅
Sample collection date	✅
Sample collection time	✅
Sample processing	✅
Sample quality	✅
Consent to use research sample	✅
Consent to share research sample

Stellenbosch COVID Kids Study

Description

Metadata collected

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