Influenzanet Digital Cohort

Study profile

Description

Influenzanet is a network of web-based surveillance systems in several European countries and monitors influenza-like Illness (ILI) in the general population. Activities in four countries (Belgium, Estonia, France, Italy) are included in VERDI. Influenzanet is a collective system of internet-based tools through which real-time surveillance of self-reported ILI in the community is undertaken. Participation is voluntary, and in any country where the platform is deployed, any member of the public can register and is then prompted on a weekly basis to report any respiratory symptoms (or lack of) during the influenza season.

Countries involved: Italy, Belgium, France, Estonia

Sample size: ~10,000 participants

Related publications:

  • McDonald SA, Jan van Hoek A, Paolotti D, Hooiveld M, Meijer A, de Lange M; Infectieradar team; van Gageldonk-Lafeber A, Wallinga J. A statistical modelling approach for determining the cause of reported respiratory syndromes from internet-based participatory surveillance when influenza virus and SARS-CoV-2 are co-circulating. PLOS Digit Health. 2024;3(12):e0000655. Published 2024 Dec 9. doi:10.1371/journal.pdig.0000655
  • Kelley K, Gozzi N, Mazzoli M, Paolotti D. Exploring influenza vaccination determinants through digital participatory surveillanceBMC Public Health. 2025;25(1):1345. Published 2025 Apr 10. doi:10.1186/s12889-025-22496-8
  • Mazzoli M, Gozzi N, Hermans L, Hens N, Carstens G, van Hoek AJ, Le Hegaret A, Guerrisi C, Turbelin C, Debin M, Colizza V, Obi C, Watson C, Dugerdil A, Flahault A, Paolotti D. Healthcare-seeking behavior and hidden influenza-like-illness across the COVID-19 pandemic: a multi-country participatory surveillance study. medRxiv 2025.10.07.25337476; doi:10.1101/2025.10.07.25337476
  • Kelley KN, Coletti P, Gozzi N, Hermans L, Mazzoli M, Paolotti D, van Hoek AJ. Towards real-time monitoring of social contacts via participatory disease surveillance. medRxiv 2025.11.17.25338859; doi:10.1101/2025.11.17.25338859
  • Calmon L, de Gaetano A, Mazzoli M, Gozzi N, Frigione G, Debin M, Turbelin C, Marmorat R, Perra N, Barrat A, Colizza V, Paolotti D. Assessing dengue knowledge, attitudes and preventive practices using participatory surveillance cohorts. medRxiv 2025.11.05.25339567; doi:10.1101/2025.11.05.25339567

Metadata collected

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 Data collected?
Demographics 
Date of birth (full or MM/YY)
Age at contact
Sex / gender
Country of birth 
Ethnic group / race / population sector 
Income level 
Employment / occupation
Other socio-economic status proxy
Education level
Civil status (‘marital’)
Locality (of health care provision)
Locality (of residence)
Household size
Household composition
  
Hospitalisation 
Admission / discharge dates or duration
Episode dates
Episode type (e.g., general; birth) 
Diagnosis (e.g., codes) 
Procedures (e.g., codes) 
Procedures dates 
Dispensed medications 
ICU admission 
Admission type (planned/emergency) 
Hospitalisation for COVID-19
  
Primary care, outpatient care 
Date of visit / contact
Diagnosis codes 
Dispensed medications codes 
Dispensed medications date 
Primary care utilisation summary 
  
Health status and exposures 
Height 
Weight 
Date of anthropometrics 
Chronic / co-morbid conditions~ 
Medications for chronic conditions
Smoker in household 
Current smoker
~ can include obesity 
  
Vaccines 
COVID-19 vaccine (timing, doses)
Type of COVID-19 vaccine
Other vaccinations / vaccination history
  
COVID-19 symptoms & contacts 
COVID-19 episodes
COVID-19 symptoms (type, severity, duration)
Influenza-like symptoms (type, timing, duration)
COVID-19 health-seeking behaviour
COVID-19 contacts in household
Medications during C-19 episode
  
Pregnancy & birth 
Date of delivery 
Length of gestation 
Birthweight 
Maternal age at delivery 
Pregnancy complications 
Smoking pre-pregnancy 
Vaccines in pregnancy (non-COVID-19) 
Parity / nulliparity 
Pre-pregnancy body mass index 
Pregnancy outcome (e.g. miscarriage) 
Mode of delivery 
Sex of baby 
Congenital anomalies 
Other newborn complications 
Placental weight 
Antenatal care usage 
Currently pregnant
  
Death 
Date of / age at death 
Cause of death 
  
COVID-19 laboratory tests 
Sample type tested
Sample / specimen collection date 
SARS-CoV-2 PCR test date 
SARS-CoV-2 PCR pos / neg result
SARS-CoV-2 PCR Ct Value 
SARS-CoV-2 LFT test date 
SARS-CoV-2 LFT test result 
Serology test date 
Serology test results 
SARS- COV-2 genomic test results 
SARS- COV-2 variant/ lineage 
Other lab tests 
  
COVID-19 sample collection / storage 
Sample type collected 
Sample collection date 
Sample collection time 
Sample processing 
Sample quality 
Consent to use research sample 
Consent to share research sample 

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